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A kinase inhibitor stops or slows down the activity of a kinase domain. Kinase domains are sections of some proteins. Everything from germs to humans has proteins with kinase domains. Proteins with kinase domains perform many jobs. For example: - They help turn sugars into energy. - They tell proteins to start or stop doing their jobs - They can pass signals within a cell. Kinase inhibitors are often drugs that stop the kinase domain from doing its job. Antibiotics are often kinase inhibitors. These drugs stop or slow down kinase proteins in bacteria that help them grow. In some cancers, kinase domains may work overtime. This can cause the cell to grow out of control. Sometimes kinase inhibitor drugs can slow or stop the cancer from growing.
Credits: All images used with permission This work was partially funded by a grant from the IMLS (LG-06-13-0180-13).